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Innovations Attempted
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1. Standardization of culture conditions and maintenance of pluripotency in bovine embryonic and spermatogonial stem cells.
2. Establishment of developmental potential of embryonic stem cell for transgenic embryo production.
3. Establishment of development potential of spermatogonial stem cells for quality semen production.
 
Our Objectives
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ESC

1. Standardization of conditions for in vitro culture of bovine embryonic and spermatogonial stem cells.
2. Characterization of stem cells using surface and intracellular markers.
3. To elucidate the differentiation potential of cultured stem cells.
4. To test the developmental competence of stem cells using in vivo mouse and bovine models.

 
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Buffalo Blastocysts

Embryonic stem (ES) cells are pluripotent cells that can be cultured indefinitely and either maintained in an undifferentiated or induced to differentiate into any cell type, including gametes. ES cells could potentially provide an unlimited source of specific, clinically important adult cells such as nerve,bone, muscle, liver or blood cells. In addition to their pluripotent capabilities [Read More]

 

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Forthcoming Events

Neural Stem Cells in Development and for Brain Repair
Date & time: 4 May 2013 - 12 May 2013
University of Milan, Italy

World Stem Cells & Regenerative Medicine Congress 2013
Date & time: 21 May 2013 - 23 May 2013
Victoria Park Plaza, London, UK

The 2013 Stem Cell Trilogy
Date & time: 4 Jun 2013 - 6 Jun 2013
The Royal Collage of Pathologists, London, UK

4th International Conference on Stem Cells and Cancer (ICSCC-2013): Proliferation, Differentiation and Apoptosis.
Date & time: 19-22 October 2013
Durbar Hall, Haffkine Institute, Parel, Mumbai, India

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Technology Developed

IVF, ETT, OPU & Cloning in large animals and methodology for transgenic embryo construction and stem cell culture establishment by detailed marker analysis for stemness and differentiation.

Success Stories

Ten cattle calves produced from a single donor in one year’s time and birth of world’s first ever buffalo calf (PRATHAM).

Project Mandate

Standardization of culture conditions for bovine embryonic and spermatogonial stem cells and their characterization and differentiation in vitro and in vivo.

Site Last Updated On

May 7th, 2013